62017Jan
Can we assess central Fontan haemodynamics using peripheral venous pressure?

Can we assess central Fontan haemodynamics using peripheral venous pressure?

The Fontan operation represents a milestone in the treatment of children born with hearts with a functionally single pumping chamber. Unfortunately the durability of the Fontan operation is limited, primarily as a consequence of the increased pressure in the general venous circulation. As such measurement of central venous and Fontan pressures is very important to…

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112016May
Mitral valve prolapse is a very common anomaly

Mitral valve prolapse is a very common anomaly

Mitral valve prolapse is a very common anomaly, seen in up to 2.4% of otherwise healthy children and adults. The occurrence is more common in some families where there are clusters of people affected by mitral valve prolapse and often with different degrees of prolapse in different members of the same family. On-going follow-up is…

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182016Apr
Respiratory rate in the first day of life of healthy newborns

Respiratory rate in the first day of life of healthy newborns

One of the questions parents ask often is whether their children breathing or heart rate are too high. This is a very important question as most current early warning scores use such variables to flag up children who may be unwell and in danger. However, breathing rate and heart rate change considerably from the newborn…

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302016Mar
Non cardiac surgery in children with congenital heart disease

Non cardiac surgery in children with congenital heart disease

Children with congenital heart disease (CHD) sometimes require surgical treatment for non cardiac problems. Actually, children with CHD are more likely to require surgery for non cardiac problems than children with no cardiac problems. This is due to the fact that not infrequently abnormalities in multiple systems can be present at the same time. In…

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152016Mar
Arrhythmias and cardiac dysfunction in Duchenne and Becker muscular dystrophy

Arrhythmias and cardiac dysfunction in Duchenne and Becker muscular dystrophy

Duchenne (DMD) and Becker muscular dystrophies (BMD) are rare inherited conditions where there is progressive skeletal muscle degeneration and loss and premature death. The conditions typically also involve the heart where the loss of muscle causes the heart to weaken and progressively fail in its pumping function. This cardiac pump failure can be detected by…

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252016Feb
Stimulation of ventricular stiffening trough the different stages of single ventricle surgery leading to the Fontan operation

Stimulation of ventricular stiffening trough the different stages of single ventricle surgery leading to the Fontan operation

The usual management for single ventricle congenital heart defects is staged surgical treatment leading to the Fontan operation. In this path, children go trough different phases or stages. Stage I is characterised by overwork of the single ventricle which has to pump blood to the lungs as well as the general circulation. With the second…

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292016Jan
Do otherwise healthy children with simple congenital cardiac defects have a higher mortality when compared to the general population?

Do otherwise healthy children with simple congenital cardiac defects have a higher mortality when compared to the general population?

Nearly 1 in 100 children is born with a congenital heart defect (CHD). Fortunately, only a minority of children have defects which require treatment over the course of their life. The remainder will only need regular medical follow-up. The absence of systematic and accurate long term follow-up data for these children and the assumption that…

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282016Jan
Association between foetal cerebral growth and congenital cardiac defects

Association between foetal cerebral growth and congenital cardiac defects

Abnormal development in children with congenital heart disease (CHD) has been very well described and is very distressing for families and carers. Many causes have been suggested, including the cardiac defect itself, the cardiac treatment received and the abnormal blood flow or oxygenation that remains after cardiac surgery in many children. The size of the…

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